Sandercock, Peter; Niewada, Maciej; Czlonkowska, Anna. (2011). International Stroke Trial database (version 2), [dataset]. University of Edinburgh. Department of Clinical Neurosciences. https://doi.org/10.7488/ds/104.
The International Stroke Trial (IST) was one of the biggest randomised trials in acute stroke. Methods: Available data on variables assessed at randomisation, at the early outcome point (14-days after randomisation or prior discharge) and at 6-months were extracted and made publically available. Results and Conclusions: The IST provides an excellent source of primary data easy-to-use for sample size calculations and preliminary analysis necessary for planning a good quality trial.
# Associated publications #
* The erratum paper explains the difference between this version ie version 2, and the previous version: Sandercock, P.A.G., Niewada, M., Członkowska, A. et al. Erratum to: The International Stroke Trial database. Trials 13, 24 (2012). https://doi.org/10.1186/1745-6215-13-24 .
* Main results paper for the trial: International Stroke Trial Collaborative Group 1997, 'The International Stroke Trial (IST): A randomised trial of aspirin, subcutaneous heparin, both, or neither among 19 435 patients with acute ischaemic stroke', The Lancet, vol. 349, no. 9065, pp. 1569-1581. https://doi.org/10.1016/S0140-6736(97)04011-7 .
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