Cousin Laboratory
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The recycling of synaptic vesicles (SVs) is central to neurotransmitter release, synaptic function and brain communication. Our laboratory studies the molecular mechanisms that control both the endocytosis and recycling of SVs. The group also investigates how presynaptic dysfunction precipitates a series of neurodegenerative and neurodevelopmental conditions and disorders of neuronal excitability.
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Macropinocyosis filopodia
Avi movie showing activity-dependent filopodia formation (measured using GPI-GFP) co-incident with SV exocytosis (measured using syp-mOr2). -
Figures 2/3 Gordon et al (2016) A fine balance of synaptophysin levels underlies efficient retrieval of synaptobrevin II to synaptic vesicles (PLOS ONE)
Data for Gordon et al (2016) PLoS One - "A fine balance of synaptophysin levels underlies efficient retrieval of synaptobrevin II to synaptic vesicles". * Figures 2 and 3 – TIFF stacks displaying the synaptobrevin ... -
Figure 4 Gordon et al (2016) A fine balance of synaptophysin levels underlies efficient retrieval of synaptobrevin II to synaptic vesicles (PLOS ONE)
Data for Gordon et al (2016) PLoS One - "A fine balance of synaptophysin levels underlies efficient retrieval of synaptobrevin II to synaptic vesicles". * Figure 4 - TIFF stacks displaying the synaptobrevin II-pHluorin ... -
Figure 1 Gordon et al (2016) A fine balance of synaptophysin levels underlies efficient retrieval of synaptobrevin II to synaptic vesicles (PLOS ONE)
Data for Gordon et al (2016) PLoS One - "A fine balance of synaptophysin levels underlies efficient retrieval of synaptobrevin II to synaptic vesicles". * Figure 1 – TIFFs displaying fluorescent images after immunostaining ...
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