Molecular, Genetic and Population Health Sciences
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Research undertaken at Molecular, Genetic and Population Health Sciences is largely based in the Institute of Genetics and Molecular Medicine, and within its component research centres (including the MRC Human Genetics Unit and the Edinburgh Cancer Research Centre) and in the Usher Institute for Population Health Sciences & Informatics.
Image: CC-BY Baldock et. al https://doi.org/10.7488/ds/749
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Institute of Genetics and Cancer
Formerly the IGMM - Institute of Genetics and Molecular Medicine -
Usher Institute
Molecular, Genetic and Population Health Sciences
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Global hospital admissions and in-hospital mortality associated with all-cause and virus-specific acute lower respiratory infections in children and adolescents aged 5-19 years between 1995 and 2019
This dataset includes the data for the paper entitled "Global hospital admissions and in-hospital mortality associated with all-cause and virus-specific acute lower respiratory infections in children and adolescents ... -
HemeLB vessel compression simulation data
This dataset contains the files to reproduce the HemeLB simulations for the effect of a vessel compression on a downstream bifurcation. In addition, one of the key outputs of the simulations is provided. -
Quantitative fetal fibronectin to improve decision making in women with signs and symptoms of preterm birth (QUIDS): Spontaneous preterm birth within 7 days risk predictor
This workbook contains anonymised data from the study Quantitative fetal fibronectin to improve decision making in women with signs and symptoms of preterm birth (QUIDS): Spontaneous preterm birth within 7 days risk predictor. -
Data pertaining to publication: Meta-GWAS Reveals Novel Genetic Variants Associated with Urinary Excretion of Uromodulin
Uromodulin, the most abundant protein excreted in normal urine, plays major roles in kidney physiology and disease. The mechanisms regulating the urinary excretion of uromodulin remain essentially unknown. We conducted a ... -
Focus Group Discussion Translations of fathers and grandmothers of children Under-Five in Pakistan
This dataset is comprised of English translations of focus group discussions of fathers and grandchildren of children under-five from selected communities in Pakistan across Islamabad, Punjab, Sindh, KPK and AJK. These ... -
In-Depth Interview Translations of mothers of children Under-Five in Pakistan
This dataset is comprised of English translations of in-depth interviews of mothers of children under-five from selected communities in Pakistan across Islamabad, Punjab, Sindh, KPK and AJK. These interviews were conducted ... -
Stakeholders' views of asthma and school-based asthma programme for primary school children: A qualitative study in Malaysia
This is a qualitative study conducted among 52 stakeholders in the education and health sectors in Malaysia. We explored the views of school staff, healthcare professionals and policymakers, about asthma and school asthma ... -
Polygenic risk scores and GWAS summary statistics for an analysis of the contribution of common risk variants to multiple sclerosis in Orkney and Shetland
Orkney and Shetland, the population isolates which make up the Northern Isles of Scotland, are of particular interest to multiple sclerosis (MS) research. While MS prevalence is high in Scotland, Orkney has the highest ... -
GWAMA summary data for morning plasma cortisol from the Cortisol Network (CORNET) Consortium 2021 (n=25,314)
The stress hormone cortisol modulates fuel metabolism, cardiovascular homoeostasis, mood, inflammation and cognition. The CORtisol NETwork (CORNET) consortium previously identified a single locus associated with morning ... -
Supplementary File 1: Key findings from downloaded COVID-19 information for those categorised as high-risk (20 April 2020)
Data supporting McClatchey et al "COVID-19 information for people living with asthma: A rapid review of publicly available information" JACI: In practice https://doi.org/10.1016/j.jaip.2021.01.003 . Abstract: In 2020, ... -
Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as a novel adiposity gene - Supplementary data
Obesity remains an unmet global health burden. Detrimental anatomical distribution of body fat is a major driver of obesity-mediated mortality risk and is demonstrably heritable. However, our understanding of the full ... -
Genetically independent phenotype analysis identifies LPA and VCAM1 as drug targets for human ageing
Data supporting the manuscript Timmers et. al (2021) bioRXiv https://doi.org/10.1101/2021.01.22.427837 . -
Ergonomic assessment of the Dix-Hallpike’s test
Abstract Objectives: Numerous tasks carried out in the otolaryngology clinic increase the chances of developing injury among practitioners. To mitigate this, we aim to observe the risk of musculoskeletal injury in ... -
SUPERSEDED - Supplementary File 1: Key findings from downloaded COVID-19 information for those categorised as high-risk (20 April 2020)
## SUPERSEDED - this item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2982 . ## Data supporting McClatchey et al "COVID-19 information for people living with asthma: A rapid review of ... -
Medication-Wide Association Study of Dementia
Dataset and code list from medication-wide association study of dementia, using the Secure Anonymised Information Linkage databank Dementia electronic Cohort (SAIL-DeC). The dataset contains the hazard ratios and p-values ... -
Summary statistics from epigenome-wide association studies and meta-analysis comparing APOE ε4 and APOE ε2 allele carriers in Generation Scotland
These datasets contain full summary statistics for epigenome-wide association studies (EWASs) carried out using two methylation samples from the Generation Scotland: Scottish Family Health Study to investigate associations ... -
Cornea resistance factor GWAS in the UK Biobank
Summary statistics from the genome-wide association study (GWAS) of cornea resistance factor (CRF) of 76,029 UK Biobank samples of British ancestry obtained through the application number 19655. The CRF analysis was ... -
Risk factors for RSV associated acute lower respiratory infection poor outcome and mortality in young children
Respiratory syncytial virus associated acute lower respiratory infection (RSV-ALRI) constitutes a substantial disease burden in young children. We aimed to identify all studies investigating the risk factors of RSV-ALRI ... -
Disease burden estimates of RSV associated with acute respiratory infections in adults with comorbidity
Respiratory syncytial virus associated acute respiratory infection (RSV-ARI) constitutes a substantial disease burden in adults, especially in those with comorbidities. We aimed to identify all studies worldwide investigating ... -
"The genetic underpinnings of adiposity: from GWAS discovery to functional characterisation" extended supplementary data
Two extended supplementary tables, needed for the submission of a thesis in fulfilment of a PhD in Precision Medicine at the University of Edinburgh in 2020. This upload includes 2 files. The first file ("TableS1_iDXA_ ...
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