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Polymer Modelling Predicts Chromosome Reorganisation in Senescence 

Chiang, Michael; Michieletto, Davide; Brackley, CA; Rattanavirotkul, Nattaphong; Mohammed, Hisham; Marenduzzo, Davide; Chandra, Tamir
This dataset contains the data related to the figures and supplemental figures in the manuscript "Polymer Modelling Predicts Chromosome Reorganisation in Senescence". Lamina-associated domains (LADs) cover a large part of ...
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Data for "Mixtures of blue phase liquid crystal with simple liquids: elastic emulsions and cubic fluid cylinders" 

Stratford, Kevin; Juho, Lintuvuori; Marenduzzo, Davide; Cates, Mike
We numerically investigate the behavior of a phase-separating mixture of a blue phase I liquid crystal with an isotropic fluid. The resulting morphology is primarily controlled by an inverse capillary number, χ, setting ...
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Nonequilibrium chromosome looping via molecular slip links 

Marenduzzo, Davide
We propose a model for the formation of chromatin loops based on the diffusive sliding of molecular slip links. These mimic the behavior of cohesinlike molecules, which, along with the CTCF protein, stabilize loops which ...
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Predicting the three-dimensional folding of cis-regulatory regions in mammalian genomes using bioinformatic data and polymer models 

Brackley, Chris A; Brown, Jill M; Waithe, Dominic; Babbs, Christian; Davies, James; Hughes, Jim R; Buckle, Veronica J; Marenduzzo, Davide
The three-dimensional organisation of chromosomes can be probed using methods such as Capture-C. However it is unclear how such population level data relates to the organisation within a single cell, and the mechanisms ...
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Interaction between Nearly Hard Colloidal Spheres at an Oil-Water Interface v2 

Muntz, Iain; Hunter, Michael; Waggett, Franceska; Bartlett, Paul; Marenduzzo, Davide; Thijssen, Job; Schofield, Andrew
We show that the interaction potential between sterically stabilised, nearly hard-sphere (PMMA-PLMA) colloids at a water-oil interface has a negligible unscreened-dipole contribution, suggesting that models previously ...
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Polymer Simulations of Heteromorphic Chromatin Predict the 3-D Folding of Complex Genomic Loci 

Buckle, Adam; Brackley, Chris A; Marenduzzo, Davide; Gilbert, Nick
This dataset contains data corresponding to the figures and supplemental figures of the manuscript "Polymer Simulations of Heteromorphic Chromatin Predict the 3-D Folding of Complex Genomic Loci". Data sets from next ...
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Swimming suppresses correlations in dilute suspensions of pusher microorganisms 

Morozov, Alexander; Skultety, Viktor; Marenduzzo, Davide
Active matter exhibits various forms of non-equilibrium states in the absence of external forcing, including macroscopic steady-state currents. Such states are often too complex to be modelled from first principles and our ...
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SUPERSEDED - Interaction between Nearly Hard Colloidal Spheres at an Oil-Water Interface 

Muntz, Iain; Thijssen, Job; Waggett, Franceska; Hunter, Michael; Schofield, Andrew; Bartlett, Paul; Marenduzzo, Davide
## This dataset has been replaced by the one which can be found at https://doi.org/10.7488/ds/2848 . ## We show that the interaction potential between sterically stabilised, nearly hard-sphere (PMMA-PLMA) colloids at a ...
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Data accompanying 'A growing bacterial colony in two dimensions as an active nematic' 

Dell'Arciprete, Dario; Blow, Matthew L; Brown, Aidan T; Farrell, Fred DC; Lintuvuori, Juho S; McVey, Alexander F; Marenduzzo, Davide; Poon, Wilson CK
How a single bacterium becomes a colony of many thousand cells is important in biomedicine and food safety. Much is known about the molecular and genetic bases of this process, but less about the underlying physical ...
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A 1-dimensional statistical mechanics model for nucleosome positioning on genomic DNA 

Tesoro, S; Ali, I; Morozov, Alexander N; Sulaiman, N; Marenduzzo, Davide
The first level of folding of DNA in eukaryotes is provided by the so-called “10-nm chromatin fibre”, where DNA wraps around histone proteins (∼10 nm in size) to form nucleosomes, which go on to create a zig-zagging ...
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Nucleosome positions alone can be used to predict domains in yeast chromosomes 

Wiese, Oliver; Marenduzzo, Davide; Brackley, Chris
Simulation data related to the project "Nucleosome positions alone can be used to predict domains in yeast chromosomes". DNA is packaged into chromosomes, which are further organized into domains: Regions of the genome ...
 

 

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Date Accessioned2020 (3)2019 (2)2018 (3)2017 (1)2016 (2)Data Creator
Marenduzzo, Davide (11)
Bartlett, Paul (2)Brackley, Chris A (2)... View allSubject ClassificationMolecular Biology Biophysics and Biochemistry (3)Physical Sciences (3)Physics (2)... View allSubject Keywordschromosome conformation (2)polymer simulations (2)Active Matter (1)... View allFunderEPSRC - Engineering and Physical Sciences Research Council (7)ERC - European Research Council (6)University of Edinburgh (3)... View allTypedataset (10)software (1)Spatial CoverageUK (2)UNITED KINGDOM (2)
 

 

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