Data extraction sheet for the systematic review of VARI-PD

Abstract

Pneumococcal disease (PD) is a major cause of communicable disease burden globally. Evidence from animal and in vitro studies suggest viral acute respiratory infection (VARI) can predispose to pneumococcal infection. Evidence from population-based studies is conflicting, possibly due to a variety of methodological challenges and problems in these studies. We conducted a systematic review of population-based studies that analysed the association between preceding seasonal VARI and subsequent PD. In the current dataset, methods and findings were summarised for each included study in Sheet 2; additionally, reasons for exclusion were given in Sheet 1.