Distributed and dynamic intracellular organization of extracellular information in yeast
Date Available
2018-06-05Type
datasetData Creator
Granados, AAPietsch, JMJ
Cepeda-Humerez, SA
Farquhar, I
Tkačik, G
Swain, P
Publisher
University of EdinburghRelation (Is Referenced By)
https://doi.org/10.1073/pnas.1716659115Metadata
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Citation
Granados, AA; Pietsch, JMJ; Cepeda-Humerez, SA; Farquhar, I; Tkačik, G; Swain, P. (2017). Distributed and dynamic intracellular organization of extracellular information in yeast, [dataset]. University of Edinburgh. https://doi.org/10.7488/ds/2214Description
Data from single-cell microscopy experiments for "Distributed and dynamic intracellular organization of extracellular information" by Granados, Pietsch, Cepeda-Humerez, Tkačik and Swain. The data come from a microfluidics-based screening of the dynamics of nuclear translocation for 10 transcription factors (Msn2, Msn4, Dot6, Tod6, Sfp1, Maf1, Mig1, Mig2, Hog1, and Yap1), which are the endpoints of evolutionarily conserved signaling pathways (including protein kinase A (PKA), AMP kinase and TOR kinase pathways). The data set includes single-cell time series describing the response of each factor for environmental transitions from rich media (2% glucose) into three different stresses: carbon stress (low glucose), osmotic stress or oxidative stress. Responses to different magnitudes of each stress are also included.The following licence files are associated with this item: