The Roslin Institute
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The Roslin Institute at the University of Edinburgh is a BBSRC-funded institute. The Institute undertakes research within the framework of BBSRC Institute Strategic Programmes focussed on the health and welfare of animals, and applications of basic animal sciences in human and veterinary medicine, the livestock industry and food security.
The Roslin Institute's mission is to gain fundamental understanding of genetic, cellular, organ and systems bioscience underpinning common mechanisms of animal development and pathology, and to drive this into prevention and treatment of important veterinary diseases and develop sustainable farm animal production systems.
The Roslin Institute aims to enhance the lives of animals and humans through world class research in animal biology.
Sub-communities within this community
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Quantitative Genetics of Complex Traits
Research strand within Genetics and Genomics at the Roslin Institute
Collections in this community
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CTLGH - Centre for Tropical Livestock Genetics and Health
Tackling global challenges through genetic improvements in tropical livestock -
Functional Genetics and Development
Formerly 'Developmental Biology' -
Thesis Data
Datasets supporting student thesis manuscripts
Recent Submissions
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Simulated metagenomic dataset for Smith et al. 2022
This dataset is simulated metagenomic data created by Rebecca (Becky) Smith, PhD student at the Roslin Institute in Mick Watson's group. This data is described in detail in Smith et al. 2022, but briefly these reads were ... -
Data from: The effects of feed restriction, time of day and time since feeding on behavioral and physiological indicators of hunger in broiler breeder hens, Poultry Science article
We used broiler breeder hens fed one of 3 feed treatments: AL (ad libitum fed), Ram (restricted, fed in the morning) and Rpm (restricted, fed in the afternoon) to control for diurnal effects. We then conducted foraging ... -
GenOMICC release 3
Here, we provide an updated analysis of the international GenOMICC study comprising a combination of microarray genotype data from 11,325 critically ill cases in the UK (9,279 cases) and Brazil (2,186), combined with ... -
GenOMICC WGS summary statistics
GWAS summary statistics from 7,491 critically ill patients from COVID-19 and 48,400 population controls: European(EUR) 5,989/42,891; South Asian(SAS) 788/3,793; African(AFR) 440/1,350; East Asian(EAS) 274/366. GWAS models ... -
SUPERSEDED - GenOMICC WGS summary statistics
## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/3411 ## GWAS summary statistics from 7,491 critically ill patients from COVID-19 and 48,400 population controls: European(EUR) ... -
Systematic map dataset of the most recent evidence on ruminant production-limiting disease prevalence and associated mortality in Ethiopia
A stable copy of the systematic map dataset of the most recent evidence on ruminant production-limiting disease prevalence and associated mortality in Ethiopia in the form of an excel file is provided here to ensure long ... -
Breeding strategies for integrating new and orphan crops in production systems
25/11/2021 Author: Jon Bancic Contact: jon.bancic@gmail.com Dataset consists of R scripts and datasets used for the analysis in Chapter 2, 3, 4 of my thesis. Each research chapter has its own directory and ... -
Synaptic and non synaptic proteome in ageing murine cortical isolates
Label free proteomic analysis of "synaptic" and "non-synaptic" mitochondrial subpopulations isolated from murine cortex throughout the process of "normal healthy" ageing. These are sub populations of mitochondria as isolated ... -
OTU table: Caecal microbiota transplantation between two different chicken broiler lines
Table describing the abundance of OTUs in samples from chicken (Ross 308) caecal samples and controls (OTUs.shared). Table describing the taxonomy of each OTU present in OTUs.shared (OTUs.taxonomy). Chickens received either ... -
Proteomic correlates of vulnerability in the presymptomatic synapse of a mouse model of SMA and a rat model of ALS Type 8
Data Generation: Tandem-mass-tagged mass-spectrometry (TMT-MS/MS) analyses of hippocampal synaptosomes of the Taiwanese mouse model of SMA, generated from n=5 each wildtype (Smn+/+), heterozygous (Smn+/-; SMN2tg/0) and ... -
A Populations Genetics Analysis of the United Kingdom's Non-Pedigree Cats
This study investigated the population genetics of 1290 UK cats. -
Minion Equine Grass Sickness Gastrointestinal Mycobiota
Minion sequencing and analysis of a gastrointestinal sample from a horse with equine grass sickness (EGS). EGS is a multiple systems neuropathy of grazing horses. To identify potential causal fungi of EGS the gastrointestinal ... -
Proteomic analysis to identify the pathways and processes affected by altered levels of Sideroflexin3 (SFXN3) in the synapse.
Proteomic data from TMT based analysis of synapses biochemically isolated from Sfxn3-KO mice (http://www.mousephenotype.org/data/genes/MGI:2137679). See attached word/.txt description for further information. Briefly ... -
GWAS hair colour
Natural hair colour within European populations is a complex genetic trait. Previous work has established that MC1R variants are the principal genetic cause of red hair colour, but with variable penetrance. Here, we have ... -
Sex-stratified linear mixed models: Non-clinical binary traits (Item 2/3)
Sex-stratified GWAS can help shed light on sexual differences in genetic architecture. In Bernabeu et al (2021) we fit sex-stratified linear mixed models (using DISSECT) across a total of 530 phenotypes to assess the effects ... -
Sex-stratified linear mixed models: Non-binary traits (Item 3/3)
Sex-stratified GWAS can help shed light on sexual differences in genetic architecture. In Bernabeu et al (2021) we fit sex-stratified linear mixed models (using DISSECT) across a total of 530 phenotypes to assess the effects ... -
Sex-stratified logistic mixed models: 42 binary traits
Sex-stratified GWAS can help shed light on sexual differences in genetic architecture. In Bernabeu et al (2021) we fit sex-stratified logistic mixed models (using REGENIE) across a total of 42 binary traits for which we’d ... -
Sex-stratified linear mixed models: Clinical binary traits (Item 1/3)
Sex-stratified GWAS can help shed light on sexual differences in genetic architecture. In Bernabeu et al (2021) we fit sex-stratified linear mixed models (using DISSECT) across a total of 530 phenotypes to assess the effects ... -
Competitive environments affect aggression of dairy cows (Bos taurus)
We examined aggressive interactions between dairy cows in a range of competitive environments associated with different resources (pasture, milking line, cubicles and feed-face) and determined their relationship with ... -
Supplementary files supporting the paper "Microarray profiling emphasizes transcriptomic differences between hippocampal in vivo tissue and in vitro cultures"
Differential expression was performed using the R package "limma" (R package version 3.44.3) (Supplementary files 1-4; 1_diff_expr_WT_cell_vs_tissue, 2_diff_expr_101LL_cell_vs_tissue, 3_diff_expr_cell_WT_ vs_101LL, ...
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