Browsing The Roslin Institute by Title
Now showing items 1-20 of 64
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2020_Thesis_SupplementaryData_s1569052_Tissue-resident immune cells in health and disease: their heterogeneity and associated gene signatures
The dataset includes supplementary figures and tables in support of the University of Edinburgh thesis titled "Tissue-resident immune cells in health and disease: their heterogeneity and associated gene signatures". -
An ADAMTS3 Missense Variant is Associated with Norwich Terrier Upper Airway Syndrome - Supporting Data
This dataset comprises of Variant Call Format (VCF) files associated with the BAM files in this publication. The full BAM files will be submitted to European Nucleotide Archive. -
Assemblies of the gyr falcon
Whole genome assemblies are crucial for understanding a wide range of aspects of falcon biology including morphology, ecology and physiology and thus essential for their care and conservation. A key aspect of the genome ... -
Assembly and validation of conserved long non-coding RNAs in the ruminant transcriptome
mRNA-like long non-coding RNAs (lncRNA) are a significant component of mammalian transcriptomes, although most are expressed only at low levels, with high tissue-specificity and/or at specific developmental stages. This ... -
Assembly of 913 microbial genomes from metagenomic sequencing of the cow rumen
This dataset represents 913 draft bacterial and archaeal genomes assembled from over 800 gigabases of rumen metagenomic sequence data derived from 43 Scottish cattle, using both metagenomic binning and Hi-C-based ... -
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Border Collie array data for 58 dogs from Illumina 170k CanineHD BeadChip
Goniodysgenesis is a developmental abnormality of the anterior chamber of the eye. It is generally considered to be congenital in dogs (Canis lupus familiaris), and has been associated with glaucoma and blindness. ... -
Canine medial coronoid process disease microarray data
The objective of this study was to identify differentially expressed genes associated with the process of medial coronoid process disease, primary to the development of osteoarthritis. The data were produced using Affymetrix ... -
Characterisation of a second gain of function EDAR variant, encoding EDAR380R, in East Asia
Bash scripts, R scripts, rehh output data. -
Characterisation of the UK honey bee metagenome
The European honey bee (Apis mellifera) plays a major role in pollination and food production, but is under threat from emerging pathogens and agro-environmental insults. As with other organisms, honey bee health is a ... -
Chicken cecal metagenome assembled genomes
We sequenced DNA from cecal contents samples taken from 24 chickens belonging to either a fast or slower growing breed consuming either a vegetable-only diet or a diet containing fish meal. We utilised 1.6T of Illumina ... -
CKCS CEL data
The dataset is microrarray data collected from canine RNA samples. The experimental design of this project is to perform comparative analysis (unpaired one-way ANOVA) between normal canine mitral valves, late stage Myxomatous ... -
Comparative profiling of murine CLN1 Thalamus and Cortex at early and late disease timepoints
CLN1 disease or Infantile neuronal ceroid lipofuscinosis is a fatal inherited neurodegenerative lysosomal storage disease of early childhood with no currently available therapy. CLN1 disease is caused by mutations in the ... -
A comparison of livestock movement network-methods and implications for disease control in developing countries
The use of network analysis to support livestock disease control in low middle-income countries (LMICs) has historically been hampered by the cost of generating empirical data in the absence of animal movement recording ... -
Comprehensive transcriptional profiling of the gastrointestinal tract of ruminants from birth to adulthood
One of the most significant physiological challenges to neonatal and juvenile ruminants is the development and establishment of the rumen. Using a subset of RNA-Seq data from our high-resolution atlas of gene expression ... -
Construction of OOEP_IVT, OOEP_CAG, OOEP_VASA and ROSA26_gRNAs plasmids
These pdf files outline the construction of the four CRISPR/Cas9 gene drive DNA plasmid constructs developed during Gus McFarlane's PhD (2016 to 2020). These files provide important supplementary information to his PhD ... -
Cow genotypes before quality control in PLINK format. Dataset pertains to manuscript "Quantitative trait loci mapping for lameness associated phenotypes in Holstein Friesian dairy cattle"
Cow genotypes in PLINK format before quality control used for a GWAS study of lameness associated phenotypes in Holstein Friesian dairy cattle. Genotypes were merged from Affymetrix and Illumina SNP chips. -
Cyclic compression of canine joint cells - microarray data
Cells are agarose embedded and cyclically compressed on FXC compression bioreactor for 4 hours followed by 24 hours of recovery incubation. RNA extracted according to Bougault et al (2008) and canine microarray performed -
Cytokine stimulation of canine chondrocytes and osteoblasts
In vitro modelling of osteoarthritis typically uses cytokines to induce a catabolic phenotype in joint cells. This model was used to identify the response to a cytokine parameter identified as most representative of early ... -
Data for "Pathogen transmission from vaccinated hosts can cause dose-dependent reduction in virulence"
# Abstract # Many livestock and increasingly human vaccines are leaky, blocking symptoms without preventing infection or onward transmission. Leakiness is concerning as it increases vaccination coverage required to ...
