Genetics and Genomics
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To advance understanding of complex animal systems and the development of improved predictive models through the application of numerical and computational approaches in the analysis, interpretation, modelling and prediction of complex animal systems from the level of the DNA and other molecules, through cellular and gene networks, tissues and organs to whole organisms and interacting populations of organisms.
Image: Detail from Fig. 1 of Regan et al.(2018) which uses data from: Regan, Tim; Freeman, Tom; Barnett, Mark. (2018). Characterisation of the UK honey bee metagenome, 2016-2017 [dataset]. The Roslin Institute. University of Edinburgh. https://doi.org/10.7488/ds/2453.
Items in this Collection
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Simulated metagenomic dataset for Smith et al. 2022
This dataset is simulated metagenomic data created by Rebecca (Becky) Smith, PhD student at the Roslin Institute in Mick Watson's group. This data is described in detail in Smith et al. 2022, but briefly these reads were ... -
GenOMICC release 3
Here, we provide an updated analysis of the international GenOMICC study comprising a combination of microarray genotype data from 11,325 critically ill cases in the UK (9,279 cases) and Brazil (2,186), combined with ... -
GenOMICC WGS summary statistics
GWAS summary statistics from 7,491 critically ill patients from COVID-19 and 48,400 population controls: European(EUR) 5,989/42,891; South Asian(SAS) 788/3,793; African(AFR) 440/1,350; East Asian(EAS) 274/366. GWAS models ... -
SUPERSEDED - GenOMICC WGS summary statistics
## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/3411 ## GWAS summary statistics from 7,491 critically ill patients from COVID-19 and 48,400 population controls: European(EUR) ... -
Breeding strategies for integrating new and orphan crops in production systems
25/11/2021 Author: Jon Bancic Contact: jon.bancic@gmail.com Dataset consists of R scripts and datasets used for the analysis in Chapter 2, 3, 4 of my thesis. Each research chapter has its own directory and ... -
OTU table: Caecal microbiota transplantation between two different chicken broiler lines
Table describing the abundance of OTUs in samples from chicken (Ross 308) caecal samples and controls (OTUs.shared). Table describing the taxonomy of each OTU present in OTUs.shared (OTUs.taxonomy). Chickens received either ... -
A Populations Genetics Analysis of the United Kingdom's Non-Pedigree Cats
This study investigated the population genetics of 1290 UK cats. -
Minion Equine Grass Sickness Gastrointestinal Mycobiota
Minion sequencing and analysis of a gastrointestinal sample from a horse with equine grass sickness (EGS). EGS is a multiple systems neuropathy of grazing horses. To identify potential causal fungi of EGS the gastrointestinal ... -
GWAS hair colour
Natural hair colour within European populations is a complex genetic trait. Previous work has established that MC1R variants are the principal genetic cause of red hair colour, but with variable penetrance. Here, we have ... -
Whole genome sequencing SNP data of honey bee drones
Genotype data from processing of whole genome sequence data for 689 honey bee drones representing samples from 14 countries and 7 subspecies. -
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GenOMICC Covid-19 summary statistics European ancestry
GWAS summary statistics for European ancestry, from the GenOMICC Covid-19 critical illness study. GWAS was performed with 1676 Europeans and 5*1676 controls and validated using 100K Genomics England controls and Generation ... -
GenOMICC Covid-19 critical illness summary statistics non-European ancestries
Non-European ancestries GWAS summary statistics for Covid-19 critical illness from the GenOMICC study -
2020_Thesis_SupplementaryData_s1569052_Tissue-resident immune cells in health and disease: their heterogeneity and associated gene signatures
The dataset includes supplementary figures and tables in support of the University of Edinburgh thesis titled "Tissue-resident immune cells in health and disease: their heterogeneity and associated gene signatures". -
XP-EHH and XP-CLR scores across water buffalo and cattle breeds
This dataset consists of XP-EHH and XP-CLR scores calculated using the hapbin (https://github.com/evotools/hapbin) and xpclr (https://github.com/hardingnj/xpclr) software with default parameters across 79 water buffalo and ... -
Gene expression in the cardiovascular system of the domestic sheep (Ovis aries)
This dataset includes gene expression estimates, from RNA-Seq, for seven cardiovascular and one skeletal muscle tissue from the sheep gene expression atlas dataset (https://journals.plos.org/plosgenetics/article?id=10.13 ... -
A comparison of livestock movement network-methods and implications for disease control in developing countries
The use of network analysis to support livestock disease control in low middle-income countries (LMICs) has historically been hampered by the cost of generating empirical data in the absence of animal movement recording ... -
A putative genomic map for resistance of Bos indicus cattle in Cameroon to bovine tuberculosis
Bovine Tuberculosis (bTB) caused by Mycobacterium bovis is a livestock disease of global economic and public health importance. There are currently no effective vaccines available for livestock and so control relies on ... -
SUPERSEDED - Water buffalo and cattle XPEHH scores across breeds
## SUPERSEDED - This dataset has been replaced by the one which can be found at https://doi.org/10.7488/ds/2849 . ## This dataset consists of XP-EHH scores calculated using the hapbin software (https://github.com/evotools/hapbin) ... -
Metagenome assembled rumen-uncultured genomes (RUGs)
DNA was sequenced from rumen contents from cattle, sheep, red deer and reindeer. We constructed 391 metagenome assembled rumen-uncultured genomes (RUGs).
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