Centre for Clinical Brain Sciences Collection
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Image: neural-progenitor-cells taken from Centre from Clinical Brain Sciences Site. Centre for Clinical Brain Sciences
Items in this Collection
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GOLD Depression Study
Inflammation has been linked to depression in the general population. People living with HIV are at three times greater risk for depression, and experience elevated inflammation despite antiretroviral therapy. We investigated ... -
Measurements of a perivascular spaces magnetic resonance imaging physical phantom and correspondent digital reference object model
Magnetic Resonance Imaging (MRI) visible perivascular spaces (PVS) have been associated with age, decline in cognitive abilities, interrupted sleep, and markers of small vessel disease. Therefore, several computational ... -
HeadOn feasibility study
This is the dataset generated from the HeadOn clinical feasibility study which examined the usability and acceptability of a digital health intervention for concussion. The study took place between November 2021 to April ... -
MATLAB-based framework for simulating and processing BOLD CVR data
Cerebrovascular reactivity (CVR) is of interest in cerebrovascular diseases to assess the health of cerebral blood vessels. This software contains MATLAB scripts designed to simulate BOLD-CVR MRI experiments using hypercapnia ... -
iRobotSurgeon Survey dataset
The iRobotSurgeon survey aimed to explore public opinion towards the issue of liability with robotic surgical systems. The survey included five hypothetical scenarios where a patient comes to harm and the respondent needs ... -
3 T BOLD CVR data from healthy volunteers suitable for within-day repeatability analyses
We aimed to assess the repeatability of CVR measurements using 3 T BOLD MRI and a fixed CO2 inspired gas challenge. Therefore, we recruited healthy volunteers. Each had two CVR scans in two separate within-day MRI sessions. ... -
Views on sharing mental and physical health data among people with and without experience of mental illness
This dataset contains responses from an online survey of 2187 participants primarily located in the UK. All participants stated that they had used the UK National Health Service (NHS) at some time in their lives. The data ... -
SUPERSEDED - Views on sharing mental and physical health data among people with and without experience of mental illness
This dataset contains responses from an online survey of 2187 participants primarily located in the UK. All participants stated that they had used the UK National Health Service (NHS) at some time in their lives. The data ... -
Charting the Impact of Bilingualism for Autistic and Non-Autistic Children
The overall aim of this research is to ask how growing up in a bilingual environment affects the linguistic, cognitive and social development of children and, importantly, do these developmental effects differ for children ... -
Metrics for quality control of results from super-resolution machine-learning algorithms – Data extracted from publications in the period 2017- May 2021
The quality enhancement and restoration of poor-quality low-resolution magnetic resonance (MR) data are paramount for improving patient care, accuracy in diagnosis and quality in clinical research. Since 2017, with the ... -
White Matter Hyperintensities Evolution Patterns 1 Year Post-lacunar Stroke and their association with post-stroke cognition
Lacunar strokes are a common type of ischemic stroke. They are associated with long-term disability, but the factors affecting the dynamic of the infarcted lesion and the brain imaging features associated with them, ... -
Systematic Review and Meta-Analysis on incidence and risk of stroke in individuals with long-term exposure to air pollutants
Exposure to air pollution is now recognized globally by governments, leading research scientists, and civil society as one of the greatest public health hazards of the 21st century. Stroke is a major cause of disability ... -
Systematic review of signal post-processing methods in blood-brain barrier dysfunction assessments via dynamic-contrast enhanced magnetic resonance imaging
DCE-MRI enables quantification of vascular permeability, but current acquisition and processing protocols may be sub-optimal. While the literature has started to recognise this is indeed a problem, decisions concerning the ... -
Systematic Review and Meta-Analysis on the Impact of Polycyclic Aromatic Hydrocarbons Exposure in Cognitive Function and Neurodegeneration in Humans
Exposure to air pollution is now recognized globally by governments, leading research scientists, and civil society as one of the greatest public health hazards of the 21st century. Polycyclic aromatic hydrocarbons (PAH) ... -
Magnetisation transfer saturation (MTsat) processing
MATLAB processing script and functions for MTsat and MTR parametric maps with example dataset and processed output. -
Associations between alcohol use and accelerated biological ageing
Data supporting the manuscript "Associations between alcohol use and accelerated biological ageing". Specifically: Genome Wide Association Study of brain age. -
Epilepsy-related mortality during the COVID-19 pandemic: a nationwide study of routine Scottish data
Methods: This was a national, population-based, cross-sectional study of routinely-collected mortality and demographic data pertaining to March–August of 2020 (COVID-19 pandemic) compared to the corresponding periods in ... -
Systematic review on the variability of the human brain arterial territories assessed using neuroimaging methods
Imaging methods for brain arterial territories have evolved significantly from cadaver injection techniques to combinations of CT angiography with multiple MRI perfusion techniques. The variability of the brain arterial ... -
Methods to quantify and visualize venules using structural magnetic resonance imaging scans
These data were part of a project to design and validate a clinically relevant method to visually assess venules from magnetic resonance imaging (MRI) structural scans, conducted primarily by Miss. Angela C.C. Jochems, ... -
Systematic Review of the Literature on Definitions and Characterisation of MS Lesions
While inspecting the brain magnetic resonance imaging (MRI) scans from a sample of Multiple Sclerosis (MS) patients, blind to any clinical, cognitive and demographic information, it caught our attention the presence of ...
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