Usher Institute general collection
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This is a general Collection for items generated from the Usher Institute but do not belong in any other existing Collection.
Items in this Collection
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HemeLB vessel compression simulation data
This dataset contains the files to reproduce the HemeLB simulations for the effect of a vessel compression on a downstream bifurcation. In addition, one of the key outputs of the simulations is provided. -
Polygenic risk scores and GWAS summary statistics for an analysis of the contribution of common risk variants to multiple sclerosis in Orkney and Shetland
Orkney and Shetland, the population isolates which make up the Northern Isles of Scotland, are of particular interest to multiple sclerosis (MS) research. While MS prevalence is high in Scotland, Orkney has the highest ... -
Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as a novel adiposity gene - Supplementary data
Obesity remains an unmet global health burden. Detrimental anatomical distribution of body fat is a major driver of obesity-mediated mortality risk and is demonstrably heritable. However, our understanding of the full ... -
"The genetic underpinnings of adiposity: from GWAS discovery to functional characterisation" extended supplementary data
Two extended supplementary tables, needed for the submission of a thesis in fulfilment of a PhD in Precision Medicine at the University of Edinburgh in 2020. This upload includes 2 files. The first file ("TableS1_iDXA_ ... -
Multivariate genomic scan implicates novel loci and haem metabolism in human ageing
Ageing phenotypes, such as years lived in good health (healthspan), total years lived (lifespan), and survival until an exceptional old age (longevity), are of interest to us all but require exceptionally large sample sizes ... -
A nation-wide retrospective, data-linkage, cohort study of epilepsy and incident dementia - supplement
Supplement to publication in Neurology. The text file holds two lists of codes used in electronic health records (hospital admission, death (ICD 10) and GP admission (ReadV2)) to classify dementia (incl. subtypes) and epilepsy. -
Optical Coherence Tomography Angiography retinal scans and segmentations
Optical Coherence Tomography Angiography retinal scans from 11 participants in the PREVENT study and associated manual segmentations of the vasculature in the scans. Optical coherence tomography angiography (OCTA) is ... -
Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances
We use a genome-wide association of 1 million parental lifespans of genotyped subjects and data on mortality risk factors to validate previously unreplicated findings near CDKN2B-AS1, ATXN2/BRAP, FURIN/FES, ZW10, PSORS1C3, ... -
Epidemiological characteristics of human-infective RNA viruses
RNA viruses are a major threat to human health. Here, based on extensive literature searches carried out over a period of 18 years, we provide a catalogue of all 214 known human-infective RNA virus species. We link these ... -
SUPERSEDED - Epidemiological characteristics of human-infective RNA viruses
## This data item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2265 . ## RNA viruses are a major threat to human health. Here, based on extensive literature searches carried out over a ... -
SUPERSEDED - Epidemiological characteristics of human-infective RNA viruses
## This item has been superseded by the one which can be found at https://doi.org/10.7488/ds/2265 . ## RNA viruses are a major threat to human health. Here, based on extensive literature searches carried out over a period ... -
Data extraction sheet for the systematic review of VARI-PD
Pneumococcal disease (PD) is a major cause of communicable disease burden globally. Evidence from animal and in vitro studies suggest viral acute respiratory infection (VARI) can predispose to pneumococcal infection. ... -
Data supporting Rubio et al on exacerbations of COPD
Please see the publication Rubio et al. ('Home monitoring of breathing rate in people with Chronic Obstructive Pulmonary Disease: observational study of feasibility, acceptability and change after exacerbation' International ... -
SUPERSEDED - Data supporting Rubio et al on exacerbations of COPD
## This dataset has been replaced by the one at https://doi.org/10.7488/ds/1981 . ##
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