Brain Network Measures and Spatial Lesion Distribution in a Sample of 47 Patients with Systemic Lupus Erythematosus (SLE)
Date Available
2019-11-28Type
datasetData Creator
Valdés Hernández, Maria delCSmith, Keith
Bastin, Mark
Amft, Nicole
Ralston, Stuart
Wardlaw, Joanna
Wiseman, Stewart
Publisher
University of Edinburgh. Centre for Clinical Brain SciencesRelation (Is Referenced By)
https://www.ncbi.nlm.nih.gov/pubmed/27687026Metadata
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Citation
Valdés Hernández, Maria del C; Smith, Keith; Bastin, Mark; Amft, Nicole; Ralston, Stuart; Wardlaw, Joanna; Wiseman, Stewart. (2019). Brain Network Measures and Spatial Lesion Distribution in a Sample of 47 Patients with Systemic Lupus Erythematosus (SLE), [dataset]. University of Edinburgh. Centre for Clinical Brain Sciences. https://doi.org/10.7488/ds/2716.Description
This dataset corresponds to a research on network organisation of brain structural connectivity in systemic lupus erythematosus (SLE) and its putative association with lesion distribution and disease indicators. White matter hyperintensity (WMH) segmentation and connectomics were performed in 47 patients with SLE from structural and diffusion magnetic resonance imaging (MRI) data. Network nodes were divided into hierarchical tiers based on numbers of connections. From each tier, and globally, brain network metrics were extracted for each patient. Voxel-based analyses of the spatial distribution of WMH in relation to disease indicators and network measures were also conducted. The data comprise all lesion distribution maps from the sample, the raw results (in nifti-1 format) of the voxel-based analyses of the WMH distribution in relation to disease indicators and network parameters, the MATLAB code to process the data, and the excel spreadsheets with the brain network metrics.The following licence files are associated with this item: