Genome-wide association summary statistics of antidepressant treatment resistance meta-analysis
Date Available
2020-03-31Type
datasetData Creator
Wigmore, EllaHafferty, Jonathan
Hall, Lynsey
Howard, David
Clarke, Toni-Kim
Fabbri, Chiara
Lewis, Cathryn
Uher, Rudolf
Navrady, Lauren
Adams, Mark
Zeng, Yanni
Campbell, Archie
Gibson, Jude
Thomson, Pippa
Hayward, Caroline
Smith, Blair
Hocking, Lynne
Padmanabhan, Sandosh
Deary, Ian
Porteous, David
Mors, Ole
Mattheisen, Manuel
Nicodemus, Kristin
McIntosh, Andrew
Publisher
University of Edinurgh. Centre for Clinical Brain Sciences. Department of PsychiatryRelation (Is Referenced By)
https://doi.org/10.1038/s41397-019-0067-3Metadata
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Citation
Wigmore, Ella; Hafferty, Jonathan; Hall, Lynsey; Howard, David; Clarke, Toni-Kim; Fabbri, Chiara; Lewis, Cathryn; Uher, Rudolf; Navrady, Lauren; Adams, Mark; Zeng, Yanni; Campbell, Archie; Gibson, Jude; Thomson, Pippa; Hayward, Caroline; Smith, Blair; Hocking, Lynne; Padmanabhan, Sandosh; Deary, Ian; Porteous, David; Mors, Ole; Mattheisen, Manuel; Nicodemus, Kristin; McIntosh, Andrew. (2020). Genome-wide association summary statistics of antidepressant treatment resistance meta-analysis, [dataset]. University of Edinurgh. Centre for Clinical Brain Sciences. Department of Psychiatry. https://doi.org/10.7488/ds/2791.Description
Data from Wigmore et al "Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP". The Pharmacogenomics Journal 20, 329–341 (2020) DOI:10.1038/s41397-019-0067-3 This dataset consists of two sets of GWAS summary statistics: - case-control analysis of treatment resistance phenotype in the Generation Scotland and GENDEP samples (inverse variance weighted meta-analysis). Cases = 358, Controls = 3855. - quantitative stages of resistance phenotype in Generation Scotland. N = 3452.
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