Summary statistics from epigenome-wide association studies and meta-analysis comparing APOE ε4 and APOE ε2 allele carriers in Generation Scotland
Date Available
2020-11-10Type
datasetData Creator
Walker, RosieVaher, Kadi
Bermingham, Mairead
Morris, Stewart
Bretherick, Andrew
Zeng, Yanni
Rawlik, Konrad
Amador, Carmen
Campbell, Archie
Haley, Chris
Hayward, Caroline
Porteous, David
McIntosh, Andrew
Marioni, Riccardo
Evans, Kathryn
Publisher
The University of EdinburghRelation (Is Referenced By)
https://doi.org/10.1101/815035Metadata
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Citation
Walker, Rosie; Vaher, Kadi; Bermingham, Mairead; Morris, Stewart; Bretherick, Andrew; Zeng, Yanni; Rawlik, Konrad; Amador, Carmen; Campbell, Archie; Haley, Chris; Hayward, Caroline; Porteous, David; McIntosh, Andrew; Marioni, Riccardo; Evans, Kathryn. (2020). Summary statistics from epigenome-wide association studies and meta-analysis comparing APOE ε4 and APOE ε2 allele carriers in Generation Scotland, [dataset]. The University of Edinburgh. https://doi.org/10.7488/ds/2948.Description
These datasets contain full summary statistics for epigenome-wide association studies (EWASs) carried out using two methylation samples from the Generation Scotland: Scottish Family Health Study to investigate associations between blood-based DNA methylation and APOE ε4 vs. ε2 carrier status. The two samples were termed the "discovery" and "replication" samples and a meta-analysis of the EWAS results from the two samples was performed. These datasets are described fully in the associated preprint, which is available on bioRxiv (https://www.biorxiv.org/content/10.1101/815035v2.full).
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