Knyzeliene, Agne; Wimberley, Catriona. (2021). Average male, female and mixed gender mouse TSPO brain maps, generated using TSPO PET radiotracer [18F]LW223 (unnormalized to injected dose), [dataset]. University of Edinburgh. College of Medicine & Veterinary Medicine. https://doi.org/10.7488/ds/2975.
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[18F]LW223 is a novel Positron Emission Tomography (PET) radiotracer which can be used to detetect 18kDa translocator protein (TSPO) distribution in vivo. Murine brain TSPO maps were generated using average SUV at 90-120 minutes post-[18F]LW223 injection in healthy male (n=9, age 14.7 ± 6.2 weeks, mean ± SD) and female (n=5, age 11.6 ± 2.5 weeks, mean ± SD) C57Bl6/J mice. Three average maps are available to download as NIfTI (.nii) files: 1) averge male TSPO map; 2) average female TSPO map; 3) average TSPO map of both sexes. The maps were smoothed using 0.2 mm Gaussian filter.
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