Our aim is to reveal how neuronal networks integrate visual information to guide perceptions and actions. We use the mouse primary visual cortex as a model system of cortical integration of sensory and non-sensory information.

By using two-photon calcium imaging combined with electrophysiological recordings in awake behaving mice, our current projects investigate:
- How visually-guided behaviour modulates neuronal activity in the visual cortex
- How individual pyramidal neurons integrate feed-forward visual inputs with contextual inputs
- How cortical information processing is impacted by metabolic state

Using such information, we apply the same combination of methods to study how this network activity is disrupted in the brain of mouse models for autistic spectrum disorders and intellectual disabilities.

See also our Github page:
https://github.com/rochefort-lab

and lab website:
https://rochefortlab.co.uk