University of Edinburgh/BHF Centre for Cardiovascular Science
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Metabolism, Obesity and Diabetes (MOD)
The MOD group brings together clinical and basic scientists with an interest in the physiology and pathophysiology of metabolic processes relevant to obesity, diabetes and cardiovascular disease. -
PiW
PET (Positron Emission Tomography) is Wonderful
Recent Submissions
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Effects of administration route on uptake kinetics of 18F‑sodium fluoride positron emission tomography in mice
18F-sodium fluoride (18F-NaF) is a positron emission tomography (PET) radiotracer widely used in skeletal imaging and has also been proposed as a biomarker of active calcification in atherosclerosis. Like most PET radiotracers, ... -
Cawthorn Lab: Data for sex differences manuscript
Source data for figures included in our manuscript about age-dependent sex differences in the metabolic effects of caloric restriction (version date 12 January 2022). The abstract is as follows: "Caloric restriction ... -
Dynamic Compartmentalisation of Intracellular Sodium in collecting duct cells
Movie S1.avi - shows localised release of sodium green from a vesicle; Movie S2.avi - shows decrease in fluorescence of vesicle over time; Movie S3.mp4 - shows increase in fluorescence of one vesicle with decrease ... -
A Systems-Level Analysis of Total-Body PET Data Reveals Complex Skeletal Metabolism Networks in vivo
Bone is now regarded to be a key regulator of a number of metabolic processes, in addition to the regulation of mineral metabolism. However, our understanding of complex bone metabolic interactions at a systems level ... -
PET Imaging experimental dataset - Victoria Morley
Data generated by Victoria Morley as part of her PhD research -
scRNA transcription profile of adult zebrafish podocytes
Background/Aims: The role of podocytes is well conserved across species from drosophila to teleosts, and mammals. Identifying the molecular markers that actively maintain the integrity of the podocyte will enable a greater ... -
Loss of Adam10 disrupts ion transport in immortalised kidney collecting duct cells
The kidney cortical collecting duct (CCD) comprises of principal cells (PC), intercalated cells (IC) and the recently discovered intermediate cell type. Kidney pathology in a mouse model of the syndrome of apparent aldosterone ... -
Average male and female mouse brain TSPO atlases, generated using TSPO PET radiotracer [18F]LW223 (normalised to injected dose)
[18F]LW223 is a novel Positron Emission Tomography (PET) radiotracer which can be used to detetect 18kDa translocator protein (TSPO) distribution in vivo. Murine brain TSPO atlases were generated using average SUV at 90-120 ... -
SUPERSEDED - Average male, female and mixed gender mouse TSPO brain maps, generated using TSPO PET radiotracer [18F]LW223 (unnormalized to injected dose)
## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2988 ## [18F]LW223 is a novel Positron Emission Tomography (PET) radiotracer which can be used to detetect 18kDa translocator ... -
Additional image (Fig 2) - Kinetic modelling and quantification bias in small animal PET studies with [18F]AB5186, a novel 18 kDa translocator protein radiotracer
This image is part of the dataset: MacAskill, Mark. (2020). Kinetic modelling and quantification bias in small animal PET studies with [18F]AB5186, a novel 18 kDa translocator protein radiotracer, [image]. University of ... -
Kinetic modelling and quantification bias in small animal PET studies with [18F]AB5186, a novel 18 kDa translocator protein radiotracer
DICOM imaging data sets, CT and PET. Distribution and kinetics of [18F]AB5186 in rats. Please note one of the images is in a separate Item in this repository, please see: MacAskill, Mark. (2020). Additional image (Fig 2) ... -
CT Image datasets for highdose 16A0XXX and 16A1XXX
High dose microCT does not contribute towards improved microPET/CT image quantitative accuracy and can limit longitudinal scanning of small animals ABSTRACT Obtaining accurate quantitative measurements in preclinical ... -
CT Image datasets for highdose 16A2XXX and 16A3XXX
High dose microCT does not contribute towards improved microPET/CT image quantitative accuracy and can limit longitudinal scanning of small animals ABSTRACT Obtaining accurate quantitative measurements in preclinical ...