Dissecting the genetic architecture of complex traits, built on expertise in molecular and quantitative genetics. Productivity, efficiency and resistance to infectious diseases are key traits of interest.

www.ed.ac.uk/roslin/research/genetics-genomics/genetics-complex-traits

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  • Sex-stratified linear mixed models: Non-clinical binary traits (Item 2/3) 

    Bernabeu, Elena; Canela-Xandri, Oriol; Rawlik, Konrad; Tenesa, Albert
    Sex-stratified GWAS can help shed light on sexual differences in genetic architecture. In Bernabeu et al (2021) we fit sex-stratified linear mixed models (using DISSECT) across a total of 530 phenotypes to assess the effects ...
  • Sex-stratified linear mixed models: Non-binary traits (Item 3/3) 

    Bernabeu, Elena; Canela-Xandri, Oriol; Rawlik, Konrad; Tenesa, Albert
    Sex-stratified GWAS can help shed light on sexual differences in genetic architecture. In Bernabeu et al (2021) we fit sex-stratified linear mixed models (using DISSECT) across a total of 530 phenotypes to assess the effects ...
  • Sex-stratified logistic mixed models: 42 binary traits 

    Bernabeu, Elena; Canela-Xandri, Oriol; Rawlik, Konrad; Tenesa, Albert
    Sex-stratified GWAS can help shed light on sexual differences in genetic architecture. In Bernabeu et al (2021) we fit sex-stratified logistic mixed models (using REGENIE) across a total of 42 binary traits for which we’d ...
  • Sex-stratified linear mixed models: Clinical binary traits (Item 1/3) 

    Bernabeu, Elena; Canela-Xandri, Oriol; Rawlik, Konrad; Tenesa, Albert
    Sex-stratified GWAS can help shed light on sexual differences in genetic architecture. In Bernabeu et al (2021) we fit sex-stratified linear mixed models (using DISSECT) across a total of 530 phenotypes to assess the effects ...