Metabolism, Obesity and Diabetes (MOD)
This DataShare Collection contains data published by researchers who are members of the Metabolism Obesity and Diabetes Theme (MOD) at the University of Edinburgh/BHF Centre for Cardiovascular Science. The MOD group brings together clinical and basic scientists with an interest in the physiology and pathophysiology of metabolic processes relevant to obesity, diabetes and cardiovascular disease. Our research covers: • Developmental processes (e.g. in utero effects; adipose cell lineage and heterogeneity), • Genetics – including utilisation of model organisms • Epigenetics and gene regulation • Mature cell function and pathogenesis (e.g. insulin resistance; insulin secretion, inflammation; hypoxia; and steroid metabolism) • Regeneration and transplant of organs that are central to metabolic homeostasis We have a particular interest in adipose tissue distribution and function and also study integrated metabolism of the liver, heart, kidney, muscle, pancreatic islets and lymphoid tissue. Our aim of the Metabolism is to act as a forum for cross-disciplinary collaborations aimed at understanding and ultimately treating cardio-metabolic diseases.
Items in this Collection
Dataset: The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent These are the source data and code underlying the figures presented in this preprint https://doi.org/10.1101/2022.02.20.481222. For further details please see the file named readme_Sex_Differences_Adipose_Tissue_Metaboli ...
*an updated version of this item can be found at https://doi.org/10.7488/ds/3758* Source data for figures included in our manuscript about age-dependent sex differences in the metabolic effects of caloric restriction ...