Gillingwater Laboratory

 

Research in the Gillingwater lab focuses on understanding cellular and molecular mechanisms that regulate the form and function of the nervous system in health and disease.

Image: CC-BY Jones RA et al https://doi.org/10.7488/ds/1490

Items in this Collection

  • Prenatal anatomical and molecular changes in a mouse model of Spinal Muscular Atrophy: thesis movies 

    Motyl, Anna
    Supplementary movies for the doctoral thesis 'Prenatal anatomical and molecular changes in a mouse model of Spinal Muscular Atrophy'. The movies illustrate the anatomical characterisation performed on embryos of a mouse ...

  • Motyl AAL, et al. (2020). Pre-symptomatic developmental phenotypes in Spinal Muscular Atrophy 

    Motyl, Anna Abigail Lydia; Gillingwater, Thomas; Wishart, Thomas
    Spinal muscular atrophy (SMA) is a leading genetic cause of infant death, characterised primarily by a loss of lower motor neurons. SMA is caused by mutations in the survival motor neuron 1 (SMN1) gene. New SMN-restoring ...

  • aNMJ-morph macro 

    Minty, Gavin; Hoppen, Alex; Boehm, Ines; Alhindi, Abrar; Gibb, Larissa; Potter, Ellie; Wagner, Boris; Miller, Janice; Skipworth, Richard; Gillingwater, Tom; Jones, Ross
    It is recommended that users of the aNMJ-morph macro are familiar with the original NMJ-morph workflow in a practical setting; please refer to the following publication for background details: "NMJ-morph reveals principal ...

  • Proteomics datasets from Shorrock et al (UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy) 

    Gillingwater, TH
    Detailed proteomics data files from Shorrock et al., 2018 'UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy' (Accepted manuscript to be published in Brain).

  • NMJ-morph 

    Jones, Ross A; Gillingwater, Thomas H
    NMJ-morph is an ImageJ-based package for morphometric analysis of the neuromuscular junction (NMJ).

  • SUPERSEDED: NMJ-morph 

    Jones, Ross A; Gillingwater, TH
    Please see the updated NMJ-morph at https://doi.org/10.7488/ds/1490 . NMJ-morph is an ImageJ-based package for morphometric analysis of the neuromuscular junction (NMJ).

  • SUPERSEDED: NMJ-morph 

    Jones, Ross A; Gillingwater, Thomas H
    Please see the updated NMJ-morph at https://doi.org/10.7488/ds/1490 . NMJ-morph is an ImageJ-based package for morphometric analysis of the neuromuscular junction (NMJ).