Data associated with publications from the Nolan Lab.

The lab's researchers are interested in molecular mechanisms that configure neural circuits to carry out computations. The approach taken combines electrophysiological, molecular and behavioural analysis, with computational modelling and development of molecular and software tools. The hope is that over the long term this research will be important for understanding and treating clinical disorders such as Alzheimer’s, schizophrenia, autism and epilepsy.

Nolan Lab

Items in this Collection

  • Grid cells are modulated by local head direction 

    Nolan, Matthew; Gerlei, Klara; Passlack, Jessica; Hawes, Ian; Vandrey, Brianna; Stevens, Holly; Papastathopoulos, Ioannis
    In vivo tetrode recordings from the medial entorhinal cortex of mice during open field exploration. This data set contains recordings from grid cells, conjunctive cells and other spatial cells. Please look at Gerlei_et_a ...
  • Inter- and intra-animal variation in the integrative properties of stellate cells in the medial entorhinal cortex 

    Pastoll, Hugh; Garden, Derek; Nolan, Matthew
    The data are whole-cell patch-clamp recordings from neurons in the medial entorhinal cortex of adult mice. The data for each neuron is a series of voltage responses to current steps or ramps injected through the recording ...
  • Fan cells in layer 2 of lateral entorhinal cortex are critical for episodic-like memory 

    Vandrey, Brianna; Garden, Derek; Ambrozova, Veronika; McClure, Christina; Nolan, Matthew; Ainge, James
    Episodic memory requires different types of information to be bound together to generate representations of experiences. The lateral entorhinal cortex (LEC) and hippocampus are required for episodic-like memory in rodents. ...
  • Stellate cells in medial entorhinal cortex are required for spatial learning 

    Tennant, Sarah; Garden, Derek; Gerlei, Klara; Martinez-Gonzalez, Cristina; McClure, Christina; Wood, Emma; Nolan, Matthew
    Spatial learning requires estimates of location that may be obtained by path integration or from positional cues. Grid and other spatial firing patterns of neurons in the superficial medial entorhinal cortex (MEC) suggest ...