• Birth weight associations with DNA methylation differences in an adult population 

      Madden, Rebecca A; McCartney, Daniel L; Hillary, Robert F; Bermingham, Mairead L; Rawlik, Konrad; Morris, Stewart W; Campbell, Archie; Porteous, David J; Deary, Ian J; Evans, Kathryn L; Hafferty, Jonathan; McIntosh, Andrew M; Marioni, Riccardo E
      The Developmental Origins Health and Disease (DOHaD) theory predicts that prenatal and early life events shape adult health outcomes. Birth weight is a useful indicator of the foetal experience, and has been associated ...
    • A Celebration of Scottish Health Cohort Studies: Participants' attitudes towards data research 

      Beange, Iona; McIntosh, Andrew; Kirkham, Elizabeth; Fletcher-Watson, Sue; Lawrie, Stephen; Batty, David; Boardman, James; Black, Corri; Porteous, David
      BACKGROUND. The UK hosts many of the world’s longest running prospective longitudinal birth cohort studies. These projects make repeated observations of their participants and use this data to explore health outcomes ...
    • Comparison of DNA methylation profiles from Generation Scotland blood samples stored on Whatman FTA cards and in EDTA tubes: EWAS summary statistics 

      Walker, Rosie; MacGillivray, Louise; McCafferty, Sarah; Wrobel, Nicola; Kerr, Shona; Morris, Stewart; Campbell, Archie; McIntosh, Andrew; Porteous, David; Evans, Kathryn
      This dataset contains summary statistics for the epigenome-wide association studies (EWASs) performed to ascertain the feasibility of profiling DNA methylation using dried blood spot (DBS) DNA from Generation Scotland ...
    • Generation Scotland Age x Sex Epigenome Wide Association Study Summary Statistics 

      McCartney, Daniel; Zhang, Futao; Hillary, Robert; Zhang, Qian; Stevenson, Anna; Walker, Rosie; Bermingham, Mairead; Boutin, Thibaud; Morris, Stewart; Campbell, Archie; Murray, Alison; Whalley, Heather; Porteous, David; Hayward, Caroline; Evans, Kathy; Chandra, Tamir; Deary, Ian; McIntosh, Andrew; Yang, Jian; Visscher, Peter; McRae, Allan; Marioni, Riccardo
      This directory contains full summary statistics for the following EWAS studies in the Generation Scotland cohort. Epigenome-wide autosomal sites associated with chronological age with concordant effect sizes in the ...
    • Generation Scotland SFHS Data Dictionary 

      Campbell, Archie; Kerr, Shona; Porteus, David
      The GS:SFHS Data Dictionary is a set of information describing the contents, format, and structure of the phenotype data collected during recruitment (2006-2011) to the Generation Scotland Scottish Family Health Study ...
    • Generation Scotland Survey Monkey data 

      Edwards, Rachel; Campbell, Archie; Porteous, David
      Generation Scotland (GS) conducted a recontact survey on ~7,000 participants who could be contacted by email. The survey used Survey Monkey Inc. to understand GS participant opinions on health research. A total of 2,316 ...
    • Generation Scotland: Donor DNA Databank 

      Kerr, Shona; Porteous, David; Campbell, Archie
      The Generation Scotland Donor DNA Databank (GS:3D) phenotype was collected from consented blood donors by questionnaire and relates to 4,998 healthy control DNA samples and plasma.
    • Genome-wide association summary statistics of antidepressant treatment resistance meta-analysis 

      Wigmore, Ella; Hafferty, Jonathan; Hall, Lynsey; Howard, David; Clarke, Toni-Kim; Fabbri, Chiara; Lewis, Cathryn; Uher, Rudolf; Navrady, Lauren; Adams, Mark; Zeng, Yanni; Campbell, Archie; Gibson, Jude; Thomson, Pippa; Hayward, Caroline; Smith, Blair; Hocking, Lynne; Padmanabhan, Sandosh; Deary, Ian; Porteous, David; Mors, Ole; Mattheisen, Manuel; Nicodemus, Kristin; McIntosh, Andrew
      Data from Wigmore et al "Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP". The Pharmacogenomics Journal ...
    • Summary statistics from epigenome-wide association studies and meta-analysis comparing APOE ε4 and APOE ε2 allele carriers in Generation Scotland 

      Walker, Rosie; Vaher, Kadi; Bermingham, Mairead; Morris, Stewart; Bretherick, Andrew; Zeng, Yanni; Rawlik, Konrad; Amador, Carmen; Campbell, Archie; Haley, Chris; Hayward, Caroline; Porteous, David; McIntosh, Andrew; Marioni, Riccardo; Evans, Kathryn
      These datasets contain full summary statistics for epigenome-wide association studies (EWASs) carried out using two methylation samples from the Generation Scotland: Scottish Family Health Study to investigate associations ...
    • SUPERSEDED - Generation Scotland SFHS Data Dictionary 

      Campbell, Archie; Kerr, Shona; Porteous, David
      ## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2277 . ## The GS:SFHS Data Dictionary is a set of information describing the contents, format, and structure of the phenotype data ...