Edinburgh Medical School
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One Health is the approach underpinning the research done at the Edinburgh Medical School. The modern challenges that face not only the UK but the world in terms of the rise of chronic disease, the shifts in populations and the challenges presented by a population which is living much longer are common and the mechanisms underpinning them are common. The aim of the School is to bring the right individuals together to catalyse and create the opportunities to really develop exciting and cutting edge clinical and non-clinical research that makes a difference to people’s lives.
Image: CC-BY Mikhael, S doi.org/10.7488/ds/1983
Sub-communities within this community
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Molecular, Genetic and Population Health Sciences
Inc the IGC (Institute of Genetics and Cancer) and the Usher Institute
Collections in this community
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John West's Research Group
Corneal epithelium research
Recent Submissions
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Development of a UPLC-MS/MS method for the simultaneous analysis of AT7519 and acetaminophen in a mouse model of acute inflammation
Targeted chromatography and mass spectrometry can be used to assess multiple compounds simultaneously and this approach has not been applied yet to measure APAP and AT7519 in a mouse model.Targeted mass spectrometry ... -
Location of CD39+ T cell sub-populations within tumours predict differential outcomes in non-small cell lung cancer
Nanostring nCounter targeted RNA Seq. data of CD4+ and CD8+ T cells isolated from human non-cancerous lung tissue and non-small cell lung cancer tumour tissue as shown in Koppensteiner et al. (in submission), "Location of ... -
Innervation of the developing kidney in vivo and in vitro
Within the adult kidney, renal neurites can be observed alongside the arteries where they play a role in regulating blood flow. However, their role and localization during development has so far not been described in detail. ... -
Data from Paper: Synaptic oligomeric tau in Alzheimer's disease - a potential culprit in the spread of tau pathology through the brain
In Alzheimer’s disease (AD), fibrillar tau pathology accumulates and spreads through the brain and synapses are lost. Evidence from mouse models indicates that tau spreads trans-synaptically from pre- to postsynapses and ... -
DecodeME Questionnaire
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a chronic disease characterised by a substantial reduction of activity levels, estimated to affect approximately 250,000 people in the UK. ME/CFS is associated ... -
Nanostring data Robertson et al. re interaction between FOXG1 and Wnt/ß-catenin signalling
GBM stem cells (GSCs) display phenotypic and molecular features reminiscent of normal neural stem cells, and exhibit a spectrum of cell cycle states (dormant, quiescent, proliferative). However, mechanisms controlling the ... -
Data from paper: Predictive blood biomarkers and brain changes associated with age-related cognitive decline
Growing evidence supports the use of plasma levels of tau phosphorylated at threonine 181 (p-tau181), amyloid-β, neurofilament light chain, and glial fibrillary acidic protein (GFAP) as promising biomarkers for Alzheimer’s ... -
The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent
These are the source data and code underlying the figures presented in the updated version of this preprint https://doi.org/10.1101/2022.02.20.481222. For further details please see the file named readme_Sex_Differences_ ... -
Validity of clinical severity scores for respiratory syncytial virus: a systematic review - data extraction sheet
The file presented is the standardised data extraction sheet that was used to extract data for the systematic review on the validity of severity scores for respiratory syncytial virus in children (≤24 months). This systematic ... -
TestEd Survey of Staff and Student Experiences and Perceptions of Novel Covid-19 Testing Platform
Survey of staff and students at the University of Edinburgh related to their participation in a routine, asymptomatic Covid-19 workplace testing pilot. 522 participants completed a pilot survey in April 2021 and 1,750 ... -
EBV serostatus and total number of siblings GWAS summary statistics
GWAS on EBV serostatus/total number of siblings on UKBiobank participants Mendelian randomisation identifies priority groups for prophylactic EBV vaccination. Marisa D. Muckian, MSc; James. F Wilson, DPhil; Graham S. ... -
cAge and bAge EWAS - Epigenome-wide association study of chronological age (linear and quadratic) and of survival
These datasets correspond to the manuscript “Refining epigenetic prediction of chronological and biological age“. Here, we include the summary statistics for an epigenome-wide association study (EWAS) of age, considering ... -
Fan cells in lateral entorhinal cortex directly influence medial entorhinal cortex through synaptic connections in layer 1
Data used to generate figures and statistical outputs for https://www.biorxiv.org/content/10.1101/2022.08.25.505296v1. Analysis code used for this dataset can be found at https://github.com/MattNolanLab/lec_to_mec. # ... -
Co-OPT: Consortium for the Study of Pregnancy Treatments: Antenatal corticosteroids cohort - Data Dictionary
This data dictionary accompanies patient data files from the ongoing Co-Opt study which are held elsewhere on secure systems. The Consortium for the Study of Pregnancy Treatments (Co-OPT) collaboration has been established ... -
Data from paper: Synaptic resilience is associated with maintained cognition during ageing
It remains unclear why age increases risk of Alzheimer’s disease and why some people experience age-related cognitive decline in the absence of dementia. Here we test the hypothesis that resilience to molecular changes in ... -
Dataset: gender representation at the Royal College of Radiologists' Annual Scientific Meeting
Deidentified dataset extracted from Royal College of Radiologists' Annual Scientific Conference programmes on genders of presenters and types of presentations. -
AAMOS-00 Study: Predicting Asthma Attacks Using Connected Mobile Devices and Machine Learning
Monitoring asthma condition is essential to asthma self-management. However, traditional methods of monitoring require high levels of active engagement and patients may regard this level of monitoring as tedious. Passive ... -
Neuronal signature of spatial decision-making during navigation by freely moving rats by using calcium imaging
See the file "dataset_description.txt". Associated publication: Gobbo, F., Mitchell-Heggs, R., Tse, D., Al-Omrani, M., Spooner, P., Shultz, S. R., & Morris, R. (2022). Neuronal signature of spatial decision-making ... -
Croatian Cohorts Data Dictionary
This Croatian biobank is family-based, cross-sectional genetics studies of population cohorts from the Island of Korcula (3000 individuals) and the mainland city of Split (1000 individuals). Blood samples were collected ... -
STROBE statement
STROBE (Strengthening the reporting of observational studies in epidemiology) statement describing the preparation of the manuscript 'Towards equality: gender representation at the Royal College of Radiologists’ Annual ...
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