Edinburgh Medical School
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One Health is the approach underpinning the research done at the Edinburgh Medical School. The modern challenges that face not only the UK but the world in terms of the rise of chronic disease, the shifts in populations and the challenges presented by a population which is living much longer are common and the mechanisms underpinning them are common. The aim of the School is to bring the right individuals together to catalyse and create the opportunities to really develop exciting and cutting edge clinical and non-clinical research that makes a difference to people’s lives.
Image: CC-BY Mikhael, S doi.org/10.7488/ds/1983
Sub-communities within this community
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Molecular, Genetic and Population Health Sciences
Institute of Genetics and Molecular Medicine and Usher Institute
Collections in this community
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John West's Research Group
Corneal epithelium research
Recent Submissions
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Qualitative study to inform intervention development for behaviour change in adults with chronic lung disease in rural India
This qualitative research informed the Theory of Planned Behaviour (TPB)-based intervention development. This dataset was generated as part of formative research conducted on patients of chronic respiratory disease (CRD), ... -
Mutational bias in spermatogonia impacts the anatomy of regulatory sites in the human genome
ATAC-Seq reports local chromatin accessibility and provides a snapshot of active regulatory regions and genomic regions occupied by DNA-binding proteins in a given tissue. We used ATAC-Seq to identify open chromatin sites ... -
Red-shifted environmental fluorophores and their use for the detection of Gram-negative bacteria_raw spectral data
Spectral data (absorption, fluorescence, lifetime) of merocyanine derivatives described in the research article entitled "Red-shifted environmental fluorophores and their use for the detection of Gram-negative bacteria" ... -
Global hospital admissions and in-hospital mortality associated with all-cause and virus-specific acute lower respiratory infections in children and adolescents aged 5-19 years between 1995 and 2019
This dataset includes the data for the paper entitled "Global hospital admissions and in-hospital mortality associated with all-cause and virus-specific acute lower respiratory infections in children and adolescents ... -
HemeLB vessel compression simulation data
This dataset contains the files to reproduce the HemeLB simulations for the effect of a vessel compression on a downstream bifurcation. In addition, one of the key outputs of the simulations is provided. -
Whose behaviour? Ca2+ imaging in medial prefrontal cortex during social dominance interactions in a Tube-Test
This data set is a supplement for the article entitled "Whose behaviour? Ca2+ imaging in medial prefrontal cortex during social dominance interactions in a Tube-Test" that is submitted for in PNAS, Saxena et al 2021. Using ... -
Quantitative fetal fibronectin to improve decision making in women with signs and symptoms of preterm birth (QUIDS): Spontaneous preterm birth within 7 days risk predictor
This workbook contains anonymised data from the study Quantitative fetal fibronectin to improve decision making in women with signs and symptoms of preterm birth (QUIDS): Spontaneous preterm birth within 7 days risk predictor. -
Loss of Adam10 disrupts ion transport in immortalised kidney collecting duct cells
The kidney cortical collecting duct (CCD) comprises of principal cells (PC), intercalated cells (IC) and the recently discovered intermediate cell type. Kidney pathology in a mouse model of the syndrome of apparent aldosterone ... -
scRNA transcription profile of adult zebrafish podocytes
Background/Aims: The role of podocytes is well conserved across species from drosophila to teleosts, and mammals. Identifying the molecular markers that actively maintain the integrity of the podocyte will enable a greater ... -
High and asymmetric somato-dendritic coupling of V1 layer 5 neurons independent of visual stimulation and locomotion
Ex vivo calibration of GCaMP6s and GCaMP6f signals in soma and apical tuft dendrites of layer 5 pyramidal neurons from the mouse primary visual cortex (V1). We examined the relationship between neuronal spiking and calcium ... -
Data pertaining to publication: Meta-GWAS Reveals Novel Genetic Variants Associated with Urinary Excretion of Uromodulin
Uromodulin, the most abundant protein excreted in normal urine, plays major roles in kidney physiology and disease. The mechanisms regulating the urinary excretion of uromodulin remain essentially unknown. We conducted a ... -
Focus Group Discussion Translations of fathers and grandmothers of children Under-Five in Pakistan
This dataset is comprised of English translations of focus group discussions of fathers and grandchildren of children under-five from selected communities in Pakistan across Islamabad, Punjab, Sindh, KPK and AJK. These ... -
In-Depth Interview Translations of mothers of children Under-Five in Pakistan
This dataset is comprised of English translations of in-depth interviews of mothers of children under-five from selected communities in Pakistan across Islamabad, Punjab, Sindh, KPK and AJK. These interviews were conducted ... -
Stakeholders' views of asthma and school-based asthma programme for primary school children: A qualitative study in Malaysia
This is a qualitative study conducted among 52 stakeholders in the education and health sectors in Malaysia. We explored the views of school staff, healthcare professionals and policymakers, about asthma and school asthma ... -
MATLAB-based framework for simulating DCE-MRI of subtle blood-brain barrier breakdown
MATLAB scripts designed to simulate a Dynamic-Contrast Enhanced (DCE)-MRI experiment with Patlak model analysis for subtle blood-brain barrier leakage pathologies e.g. cerebral small vessel disease. This simulation framework ... -
Polygenic risk scores and GWAS summary statistics for an analysis of the contribution of common risk variants to multiple sclerosis in Orkney and Shetland
Orkney and Shetland, the population isolates which make up the Northern Isles of Scotland, are of particular interest to multiple sclerosis (MS) research. While MS prevalence is high in Scotland, Orkney has the highest ... -
Average male and female mouse brain TSPO atlases, generated using TSPO PET radiotracer [18F]LW223 (normalised to injected dose)
[18F]LW223 is a novel Positron Emission Tomography (PET) radiotracer which can be used to detetect 18kDa translocator protein (TSPO) distribution in vivo. Murine brain TSPO atlases were generated using average SUV at 90-120 ... -
GWAMA summary data for morning plasma cortisol from the Cortisol Network (CORNET) Consortium 2021 (n=25,314)
The stress hormone cortisol modulates fuel metabolism, cardiovascular homoeostasis, mood, inflammation and cognition. The CORtisol NETwork (CORNET) consortium previously identified a single locus associated with morning ... -
Supplementary File 1: Key findings from downloaded COVID-19 information for those categorised as high-risk (20 April 2020)
Data supporting McClatchey et al "COVID-19 information for people living with asthma: A rapid review of publicly available information" JACI: In practice https://doi.org/10.1016/j.jaip.2021.01.003 . Abstract: In 2020, ... -
SUPERSEDED - Average male, female and mixed gender mouse TSPO brain maps, generated using TSPO PET radiotracer [18F]LW223 (unnormalized to injected dose)
## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2988 ## [18F]LW223 is a novel Positron Emission Tomography (PET) radiotracer which can be used to detetect 18kDa translocator ...
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