Edinburgh Medical School
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One Health is the approach underpinning the research done at the Edinburgh Medical School. The modern challenges that face not only the UK but the world in terms of the rise of chronic disease, the shifts in populations and the challenges presented by a population which is living much longer are common and the mechanisms underpinning them are common. The aim of the School is to bring the right individuals together to catalyse and create the opportunities to really develop exciting and cutting edge clinical and non-clinical research that makes a difference to people’s lives.
Image: CC-BY Mikhael, S doi.org/10.7488/ds/1983
Sub-communities within this community
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Molecular, Genetic and Population Health Sciences
Institute of Genetics and Molecular Medicine and Usher Institute
Collections in this community
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John West's Research Group
Corneal epithelium research
Recent Submissions
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Polygenic risk scores and GWAS summary statistics for an analysis of the contribution of common risk variants to multiple sclerosis in Orkney and Shetland
Orkney and Shetland, the population isolates which make up the Northern Isles of Scotland, are of particular interest to multiple sclerosis (MS) research. While MS prevalence is high in Scotland, Orkney has the highest ... -
Average male and female mouse brain TSPO atlases, generated using TSPO PET radiotracer [18F]LW223 (normalised to injected dose)
[18F]LW223 is a novel Positron Emission Tomography (PET) radiotracer which can be used to detetect 18kDa translocator protein (TSPO) distribution in vivo. Murine brain TSPO atlases were generated using average SUV at 90-120 ... -
GWAMA summary data for morning plasma cortisol from the Cortisol Network (CORNET) Consortium 2021 (n=25,314)
The stress hormone cortisol modulates fuel metabolism, cardiovascular homoeostasis, mood, inflammation and cognition. The CORtisol NETwork (CORNET) consortium previously identified a single locus associated with morning ... -
Supplementary File 1: Key findings from downloaded COVID-19 information for those categorised as high-risk (20 April 2020)
Data supporting McClatchey et al "COVID-19 information for people living with asthma: A rapid review of publicly available information" JACI: In practice https://doi.org/10.1016/j.jaip.2021.01.003 . Abstract: In 2020, ... -
SUPERSEDED - Average male, female and mixed gender mouse TSPO brain maps, generated using TSPO PET radiotracer [18F]LW223 (unnormalized to injected dose)
## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2988 ## [18F]LW223 is a novel Positron Emission Tomography (PET) radiotracer which can be used to detetect 18kDa translocator ... -
Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as a novel adiposity gene - Supplementary data
Obesity remains an unmet global health burden. Detrimental anatomical distribution of body fat is a major driver of obesity-mediated mortality risk and is demonstrably heritable. However, our understanding of the full ... -
Genetically independent phenotype analysis identifies LPA and VCAM1 as drug targets for human ageing
Data supporting the manuscript Timmers et. al (2021) bioRXiv https://doi.org/10.1101/2021.01.22.427837 . -
Ergonomic assessment of the Dix-Hallpike’s test
Abstract Objectives: Numerous tasks carried out in the otolaryngology clinic increase the chances of developing injury among practitioners. To mitigate this, we aim to observe the risk of musculoskeletal injury in ... -
SUPERSEDED - Supplementary File 1: Key findings from downloaded COVID-19 information for those categorised as high-risk (20 April 2020)
## SUPERSEDED - this item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2982 . ## Data supporting McClatchey et al "COVID-19 information for people living with asthma: A rapid review of ... -
A four-dimensional computational model of dynamic contrast-enhanced magnetic resonance imaging measurement of subtle blood-brain barrier leakage: source code
Computational model from the article: Bernal, J.; Valdés-Hernández, M.; Escudero, J.; Heye, A.; Sakka, E.; Armitage, P.; Makin, S.; Touyz, R.; Wardlaw, J.; Thrippleton, M. A Four-Dimensional Computational Model of Dynamic ... -
Source code and example data for "Open source image processing methods for real-time fibre bundle optical endomicroscopy"
The dataset contains source code in C++ (with OpenCV) and MATLAB (with Image Processing Toolbox) to process images acquired by Optical Endomicroscopy (OEM) with imaging fibre bundles. Example images of human and porcine ... -
Medication-Wide Association Study of Dementia
Dataset and code list from medication-wide association study of dementia, using the Secure Anonymised Information Linkage databank Dementia electronic Cohort (SAIL-DeC). The dataset contains the hazard ratios and p-values ... -
Summary statistics from epigenome-wide association studies and meta-analysis comparing APOE ε4 and APOE ε2 allele carriers in Generation Scotland
These datasets contain full summary statistics for epigenome-wide association studies (EWASs) carried out using two methylation samples from the Generation Scotland: Scottish Family Health Study to investigate associations ... -
Cornea resistance factor GWAS in the UK Biobank
Summary statistics from the genome-wide association study (GWAS) of cornea resistance factor (CRF) of 76,029 UK Biobank samples of British ancestry obtained through the application number 19655. The CRF analysis was ... -
Risk factors for RSV associated acute lower respiratory infection poor outcome and mortality in young children
Respiratory syncytial virus associated acute lower respiratory infection (RSV-ALRI) constitutes a substantial disease burden in young children. We aimed to identify all studies investigating the risk factors of RSV-ALRI ... -
Disease burden estimates of RSV associated with acute respiratory infections in adults with comorbidity
Respiratory syncytial virus associated acute respiratory infection (RSV-ARI) constitutes a substantial disease burden in adults, especially in those with comorbidities. We aimed to identify all studies worldwide investigating ... -
Data and code for Core crosstalk in ordered imaging fibre bundles
Data and code for the paper: "Core crosstalk in ordered imaging fibre bundles" Parker, H, et al. (Accepted manuscript). -
Supplementary material for paper "Time-resolved spectroscopy of fluorescence quenching in optical fibre-based pH sensors"
Abstract: Numerous optodes, with fluorophores as the chemical sensing element and optical fibres for light delivery and collection, have been fabricated for minimally invasive endoscopic measurements of key physiological ... -
Additional image (Fig 2) - Kinetic modelling and quantification bias in small animal PET studies with [18F]AB5186, a novel 18 kDa translocator protein radiotracer
This image is part of the dataset: MacAskill, Mark. (2020). Kinetic modelling and quantification bias in small animal PET studies with [18F]AB5186, a novel 18 kDa translocator protein radiotracer, [image]. University of ... -
"The genetic underpinnings of adiposity: from GWAS discovery to functional characterisation" extended supplementary data
Two extended supplementary tables, needed for the submission of a thesis in fulfilment of a PhD in Precision Medicine at the University of Edinburgh in 2020. This upload includes 2 files. The first file ("TableS1_iDXA_ ...
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