College of Medicine & Veterinary Medicine
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The University of Edinburgh’s College of Medicine & Veterinary Medicine is an international leader in basic-to-clinical translational research. The College's research ranges from bench to bedside and from process to population. Research themes are: genes and populations, normal and diseased cells and inflammation and tissue repair.
The University is one of the oldest centres for medical and veterinary medical research in the UK. It is also one of the most dynamic and progressive, with state of the art facilities across the College. The 2014 Research Excellence Framework (REF) results reaffirmed the College’s reputation as one of the world’s leading centres of medical and veterinary medical research.
College of Medicine & Veterinary Medicine
Image: CC-BY Henstridge et al DOI: 10.7488/ds/1414
Sub-communities within this community
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Centre for Clinical Brain Sciences
Research into the causes, consequences and treatment of major brain disorders -
Edinburgh Medical School
Bringing together Biomedical Sciences, Clinical Sciences, Molecular, Genetic and Population Health Sciences -
Royal (Dick) School of Veterinary Studies
School of Veterinary Studies and the Roslin Institute
Recent Submissions
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Systematic Review and Meta-Analysis on the Impact of Polycyclic Aromatic Hydrocarbons Exposure in Cognitive Function and Neurodegeneration in Humans
Exposure to air pollution is now recognized globally by governments, leading research scientists, and civil society as one of the greatest public health hazards of the 21st century. Polycyclic aromatic hydrocarbons (PAH) ... -
Human Brain Atlases across the lifespan – Anatomical Segmentations
Dickie and colleagues generated seven age-specific brain tissue sets/atlases of T1-weighted brain MRI illustrative of the adult lifespan from 25 to 92 years, which are representative of the atrophy and neurovascular health ... -
Whose behaviour? Ca2+ imaging in medial prefrontal cortex during social dominance interactions in a Tube-Test
This data set is a supplement for the article entitled "Whose behaviour? Ca2+ imaging in medial prefrontal cortex during social dominance interactions in a Tube-Test" that is submitted for in PNAS, Saxena et al 2021. Using ... -
Quantitative fetal fibronectin to improve decision making in women with signs and symptoms of preterm birth (QUIDS): Spontaneous preterm birth within 7 days risk predictor
This workbook contains anonymised data from the study Quantitative fetal fibronectin to improve decision making in women with signs and symptoms of preterm birth (QUIDS): Spontaneous preterm birth within 7 days risk predictor. -
scRNA transcription profile of adult zebrafish podocytes
Background/Aims: The role of podocytes is well conserved across species from drosophila to teleosts, and mammals. Identifying the molecular markers that actively maintain the integrity of the podocyte will enable a greater ... -
Loss of Adam10 disrupts ion transport in immortalised kidney collecting duct cells
The kidney cortical collecting duct (CCD) comprises of principal cells (PC), intercalated cells (IC) and the recently discovered intermediate cell type. Kidney pathology in a mouse model of the syndrome of apparent aldosterone ... -
Supplementary files supporting the paper "Microarray profiling emphasizes transcriptomic differences between hippocampal in vivo tissue and in vitro cultures"
Differential expression was performed using the R package "limma" (R package version 3.44.3) (Supplementary files 1-4; 1_diff_expr_WT_cell_vs_tissue, 2_diff_expr_101LL_cell_vs_tissue, 3_diff_expr_cell_WT_ vs_101LL, ... -
Microarray data CEL files supporting the paper "Microarray profiling emphasizes transcriptomic differences between hippocampal in vivo tissue and in vitro cultures"
Affymetrix microarray processing produced 16 (4 WT cell, 4 101LL cell, 4 WT tissue, 4 101LL tissue) probe cell intensity data (CEL) files. Primary hippocampal cell cultures are routinely used as an experimentally accessible ... -
High and asymmetric somato-dendritic coupling of V1 layer 5 neurons independent of visual stimulation and locomotion
Ex vivo calibration of GCaMP6s and GCaMP6f signals in soma and apical tuft dendrites of layer 5 pyramidal neurons from the mouse primary visual cortex (V1). We examined the relationship between neuronal spiking and calcium ... -
Data pertaining to publication: Meta-GWAS Reveals Novel Genetic Variants Associated with Urinary Excretion of Uromodulin
Uromodulin, the most abundant protein excreted in normal urine, plays major roles in kidney physiology and disease. The mechanisms regulating the urinary excretion of uromodulin remain essentially unknown. We conducted a ... -
Focus Group Discussion Translations of fathers and grandmothers of children Under-Five in Pakistan
This dataset is comprised of English translations of focus group discussions of fathers and grandchildren of children under-five from selected communities in Pakistan across Islamabad, Punjab, Sindh, KPK and AJK. These ... -
In-Depth Interview Translations of mothers of children Under-Five in Pakistan
This dataset is comprised of English translations of in-depth interviews of mothers of children under-five from selected communities in Pakistan across Islamabad, Punjab, Sindh, KPK and AJK. These interviews were conducted ... -
Stakeholders' views of asthma and school-based asthma programme for primary school children: A qualitative study in Malaysia
This is a qualitative study conducted among 52 stakeholders in the education and health sectors in Malaysia. We explored the views of school staff, healthcare professionals and policymakers, about asthma and school asthma ... -
Antigenic diversity in Theileria parva populations from cattle and African buffalo analysed using long read sequencing
East Coast fever (ECF) in cattle is caused by the tick-borne protozoan Theileria parva, and is transmitted by the three-host tick Rhipicephalus appendiculatus. The African buffalo (Syncerus caffer) is the natural host for ... -
MATLAB-based framework for simulating DCE-MRI of subtle blood-brain barrier breakdown
MATLAB scripts designed to simulate a Dynamic-Contrast Enhanced (DCE)-MRI experiment with Patlak model analysis for subtle blood-brain barrier leakage pathologies e.g. cerebral small vessel disease. This simulation framework ... -
Whole genome sequencing SNP data of honey bee drones
Genotype data from processing of whole genome sequence data for 689 honey bee drones representing samples from 14 countries and 7 subspecies. -
Polygenic risk scores and GWAS summary statistics for an analysis of the contribution of common risk variants to multiple sclerosis in Orkney and Shetland
Orkney and Shetland, the population isolates which make up the Northern Isles of Scotland, are of particular interest to multiple sclerosis (MS) research. While MS prevalence is high in Scotland, Orkney has the highest ... -
Average male and female mouse brain TSPO atlases, generated using TSPO PET radiotracer [18F]LW223 (normalised to injected dose)
[18F]LW223 is a novel Positron Emission Tomography (PET) radiotracer which can be used to detetect 18kDa translocator protein (TSPO) distribution in vivo. Murine brain TSPO atlases were generated using average SUV at 90-120 ... -
GWAMA summary data for morning plasma cortisol from the Cortisol Network (CORNET) Consortium 2021 (n=25,314)
The stress hormone cortisol modulates fuel metabolism, cardiovascular homoeostasis, mood, inflammation and cognition. The CORtisol NETwork (CORNET) consortium previously identified a single locus associated with morning ... -
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