Browsing College of Medicine & Veterinary Medicine by Date Accessioned
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International Stroke Trial database (superseded)
(University of Edinburgh. Department of Clinical Neurosciences, 2010-09-24)## This dataset has been replaced by the one which can be found at https://doi.org/10.7488/ds/104 . ## The International Stroke Trial (IST) was one the biggest randomised trials in acute stroke. Methods: Available data ... -
International Stroke Trial database (version 2)
(University of Edinburgh. Department of Clinical Neurosciences, 2011-11-02)The International Stroke Trial (IST) was one of the biggest randomised trials in acute stroke. Methods: Available data on variables assessed at randomisation, at the early outcome point (14-days after randomisation or prior ... -
A genome-wide screen in human embryonic stem cells reveals novel sites of allele-specific histone modification associated with known disease loci
(2012-10-31)Background Chromatin structure at a given site can differ between chromosome copies in a cell, and such imbalances in chromatin structure have been shown to be important in understanding the molecular mechanisms controlling ... -
Identification of miRNAs associated with the follicular-luteal transition in the ruminant ovary
(University of Edinburgh. Roslin Institute, 2013-03-26)Little is known about the involvement of microRNAs (miRNAs) in the follicular-luteal transition. The aim of this study was to identify genome-wide changes in miRNAs associated with follicular differentiation in sheep. miRNA ... -
Stress hyperglycaemia in hospitalised patients and their 3-year risk of diabetes: A Scottish Retrospective cohort study
(University of Edinburgh. Centre for Population Health Sciences, 2014-08-11)Background: Hyperglycaemia during hospital admission is common in patients who are not known to have diabetes and is associated with adverse outcomes. The risk of subsequently developing type 2 diabetes, however, is not ... -
SUPERSEDED: NMJ-morph
Please see the updated NMJ-morph at http://datashare.is.ed.ac.uk/handle/10283/1907 . NMJ-morph is an ImageJ-based package for morphometric analysis of the neuromuscular junction (NMJ). -
RNA composition metrics
Mutating RNA virus genomes to alter codon pair (CP) frequencies and reduce translation efficiency has been advocated as a method to generate safe, attenuated virus vaccines. However, selection for disfavoured CPs leads to ... -
A test-retest fMRI dataset for motor, language and spatial attention functions
A test-retest dataset was acquired to validate fMRI tasks used in pre-surgical planning. In particular, five task-related fMRI time series (finger, foot and lip movement, overt verb generation, covert verb generation, overt ... -
Lagging strand replication shapes the mutational landscape of the genome
The origin of mutations is central to understanding evolution and of key relevance to health. Variation occurs non-randomly across the genome, and mechanisms for this remain to be defined. Here we report that the 5' ends ... -
hapbin: An efficient program for performing haplotype based scans for positive selection in large genomic datasets
These files contain genome-wide integrated haplotype scores (iHS) for each of the 26 populations in the phase 3 release of the 1000 genomes project. iHS were calculated using the hapbin program that can be downloaded from ... -
IgM antibodies exhibit preferential binding to apoptotic and non-apoptotic nucleated cells
Data set characterising IgM antibody binding to non-apoptotic, apoptotic and permeable murine/human thymocytes and murine erythrocytes. Methodology used consisted of flow cytometry, confocal and electron microscopy. With ... -
The human Voice Areas: spatial organisation and inter-individual variability in temporal and extra-temporal cortices.
Abstract: FMRI studies increasingly examine functions and properties of non-primary areas of human auditory cortex. However there is currently no standardized localization procedure to reliably identify specific areas ... -
Archiving and Sharing Functional MRI data
This document describes the file structure and metadata requirements followed in the collating of Edinburgh Imaging fMRI results and their preparation for online sharing, as at July 2015. -
Generation Scotland: Donor DNA Databank
The Generation Scotland Donor DNA Databank (GS:3D) phenotype was collected from consented blood donors by questionnaire and relates to 4,998 healthy control DNA samples and plasma. -
Carboxy Terminus Heat shock Protein 70 interacting Protein reduces tau-associated degenerative changes
One of the hallmarks of Alzheimer’s Disease is the formation of Neurofibrillary Tangles (NFTs), intracellular aggregates of hyperphosphorylated, mislocalized tau protein, which are associated with neuronal loss. Changes ... -
Array Tomography Movie
Video of array tomography procedure with brain tissue carried out as part of the research described in Kay et al http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712649/ . -
Somatic Cell Nuclear Transfer (Cloning) Efficiency
Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation ... -
eHistology Kaufman Atlas Plate 15a image g
The eMouseAtlas team have re-digitised the original histological sections used for the "Atlas of Mouse Development" by Matt Kaufman. The resource is published available on the Web at http://www.emouseatlas.org/emap/eHistology/ ... -
eHistology Kaufman Atlas Plate 15a image h
The eMouseAtlas team have re-digitised the original histological sections used for the "Atlas of Mouse Development" by Matt Kaufman. The resource is published available on the Web at http://www.emouseatlas.org/emap/eHistology/ ...
