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Proteomic profiling of primate synapses during normal healthy ageing

Wishart, Thomas

Normal mammalian brain ageing is characterised by the selective loss of discrete populations of dendritic spines and synapses, particularly affecting neuroanatomical regions such as the hippocampus. Although previous ...

Genetically independent phenotype analysis identifies LPA and VCAM1 as drug targets for human ageing

Timmers, PRHJ; Tiys, ES; Sakaue, S; Akiyama, M; Kiiskinen, TTJ; Zhou, W; Hwang, S; Yao, C; Biobank Japan Project, The; FinnGen Study, The; Deelen, J; Levy, D; Ganna, A; Okada, Y; Joshi, PK; Wilson, JF; Tsepilov, YA

Data supporting the manuscript Timmers et. al (2021) bioRXiv https://doi.org/10.1101/2021.01.22.427837 .