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Multivariate genomic scan implicates novel loci and haem metabolism in human ageing

Timmers, Paul RHJ; Wilson, James F; Joshi, Peter K; Deelen, Joris

Ageing phenotypes, such as years lived in good health (healthspan), total years lived (lifespan), and survival until an exceptional old age (longevity), are of interest to us all but require exceptionally large sample sizes ...

Genetically independent phenotype analysis identifies LPA and VCAM1 as drug targets for human ageing

Timmers, PRHJ; Tiys, ES; Sakaue, S; Akiyama, M; Kiiskinen, TTJ; Zhou, W; Hwang, S; Yao, C; Biobank Japan Project, The; FinnGen Study, The; Deelen, J; Levy, D; Ganna, A; Okada, Y; Joshi, PK; Wilson, JF; Tsepilov, YA

Data supporting the manuscript Timmers et. al (2021) bioRXiv https://doi.org/10.1101/2021.01.22.427837 .